How to use volumes accumulation and market profile? When you asked it it's mean that you understood that , most of different kind of EA and indicators don't work well. You are on the right track. Volumes and prices are pure information which we received from Exchanges. And we could use more effective then other information which are derivatives from the prices and/or volumes. How we can trade it? This is no so big secrets. You should mark  big areas of  volumes accumulation. And usually price is move from one area to another.

There are two kind of price condition. Balance and imbalance. When price has reached volume of accumulation they usually working with it and start building new balance zone. When zone of balance builded price go out from it  to another zone of balance where start built new zone. When you have know where located frontiers it is very easy to trade from them. You can put small stop loss and expect for bigger profit. There are few examples how we do it.